Evaluate the effectiveness and safety of Lactobacillus delbrueckii subsp. bulgaricus LB42 as a food supplement compared to a placebo in improving intestinal and immune functions in healthy adults.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
52
The experimental phase of this study will last 8 weeks and each subject will receive 3 follow-up visits (week 0, week 4, week 8).
The experimental phase of this study will last 8 weeks and each subject will receive 3 follow-up visits (week 0, week 4, week 8).
Xu fei
Zhengzhou, Henan, China
Change in the concentration of LL-37 in feces before and after intervention.
Detected by Enzyme-Linked Immunosorbent Assay (ELISA).
Time frame: Week 0 and Week 8
Change in the composition of fecal microbiota before and after intervention.
Analyzed by 16s RNA sequencing.
Time frame: Week 0 and Week 8
Change in the concentration of calprotectin in feces before and after intervention.
Detected by Enzyme-Linked Immunosorbent Assay (ELISA).
Time frame: Week 0 and Week 8
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