Phase 2b Study of EVO756 in Adults With Moderate to Severe Chronic Spontaneous Urticaria (CSU)

Inclusion Criteria: * Confirmed CSU diagnosis for at least 3 months with an inadequate response to H1-antihistamines. * Subjects who are taking H1-antihistamines must be on a stable regimen 4 weeks prior to Day 1 and while on study. * Urticaria Activity Score (UAS7) equal to or greater than 16 at Day 1. UAS entries must be completed for a minimum of 4 out of the 7 days prior to Day 1. Exclusion Criteria: * Any clinically significant abnormality in laboratory evaluations, physical examinations, vital signs, or ECG at Screening, according to the Investigator's discretion. * Use of certain medications. * History of diseases with urticaria or angioedema symptoms, other than CSU and symptomatic dermographism. * Significant medical history other than CSU, or any other condition which might interfere with the evaluation of CSU.