This study aims to evaluate the effects of pre-intubation oropharyngeal topical lidocaine on optic nerve sheath diameter (ONSD) post-endotracheal intubation. The study will measure the ONSD using ultrasonography before intubation, and at 1, 5, and 10 minutes post-intubation. The results will be compared between patients receiving %10 lidocaine topically and %2 intravenous lidocaine.
Increased intracranial pressure (ICP) is a critical condition that requires early and accurate assessment. Traditional invasive ICP monitoring techniques, such as lumbar puncture and intracranial pressure monitoring devices, carry significant risks. Optic nerve sheath diameter (ONSD) measurement via ultrasonography is a non-invasive method that reflects increased ICP. Patients will be divided into two groups: Group A will receive %10 topical oropharyngeal lidocaine, and Group B will receive %2 intravenous lidocaine. The primary aim of the study is to evaluate the impact of lidocaine on ONSD at 1, 5, and 10 minutes post-intubation and to compare the effects on the two groups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
TRIPLE
Enrollment
190
optic nerve sheath diameter (ONSD) measured via ultrasonography before intubation
optic nerve sheath diameter measurement 1 via ultrasonography after intubation 1st minute
optic nerve sheath diameter measurement via ultrasonography after intubation 5th minute
Ankara Bilkent City Hospital
Ankara, Turkey, Turkey (Türkiye)
Optic nerve sheath diameter 0
optic nerve sheath diameter (ONSD) measured via ultrasonography before intubation
Time frame: Before intubation
Optic nerve sheath diameter 1
optic nerve sheath diameter (ONSD) measured via ultrasonography 1 minute after intubation
Time frame: 1 minute after intubation
Optic nerve sheath diameter 2
Optic nerve sheath diameter (ONSD) measured via ultrasonography 5 minutes after intubation
Time frame: 5 minutes after intubation
0ptic nerve sheath diameter 3
0ptic nerve sheath diameter (ONSD) measured via ultrasonography 10th minutes after intubation
Time frame: 10th minutes after intubation
Postoperative sore throat
Postoperative sore throat is evaluated with Visual Analog scale
Time frame: 1 hour after recovery room admission
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optic nerve sheath diameter measurement via ultrasonography after intubation 10th minute
Pre-intubation oropharyngeal topical %10 lidocaine
Pre-intubation intravenous %2 lidocaine