The goal of this observational study is to determine the relationship of ROTEM point-of-care coagulation assay parameters with excessive bleeding and clinical outcomes in patients undergoing cardiac surgery at Toronto General Hospital. The main questions it aims to answer are: i) How well does viscoelastic testing (VET) predict the clinical outcome of excessive bleeding in cardiac surgery? ii) Which VET parameters have the greatest accuracy for identification of patients who will have excessive bleeding? iii) 3) What is the prognostic value of abnormal VET parameters with other clinical outcomes after cardiac surgery?
Study Type
OBSERVATIONAL
Enrollment
15,000
This is an observational study. No intervention.
Excessive bleeding
Measured by the universal definition of perioperative bleeding (UDPB) scale
Time frame: From the end of bypass to the end of postoperative day-1 (POD1)
Transfusion rate
Incidence and amount of transfusion of allogeneic blood products and factor concentrates
Time frame: 1) From time of entry to operating room (OR) to the end of post-operative day-1 (POD1) and post-operative day-7(POD7). 2) from end of cardiopulmonary bypass (CPB) to the end of post-operative day-1 (POD1) and post-operative day-7 (POD7)
Deep Grewal
CONTACT
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