Probiotics will be used for preterm infants under 32 weeks of gestation and under 1500 g birthweight. Our aim was to investigate the effects of probiotics for stable preterm infants after extubation and who reached full enteral feeding. There are some hesitations among care-givers to start probiotics early due to safety issues although there are many positive effects of these products reported int the literature.
Our study included premature babies with a birth weight of less than 1500 grams, born at less than 32 weeks of gestation, and without congenital anomalies. Approval was obtained from the hospital's clinical research ethics committee before starting the study. The decision to start probiotics was made when these premature babies were fully enteral fed. The study design was created as a cohort and case-control study (No randomisation). When clinicians decided to start probiotic support for premature babies with good general health and no additional problems, probiotics were added to the baby's order.
Study Type
OBSERVATIONAL
Enrollment
100
Bifidobacterium containing supplement with vitamin D will start after preterm infants reaches full enteral feeding
Rather than early period we will start probiotics after infant receive full enteral feedings
Antropometric measures
daily weight gain mg/kg/day
Time frame: 2 months
Metabolic profile
Ca, P, ALP, Urea and biochmeical markers for nutritional status
Time frame: 2 months
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