This study aimed to compare WHO treatment of acute watery diarrhea with or without probiotic (bacillus clausii) in term of mean duration of diarrhea in children
Available literature regarding the use of probiotics is not conclusive and contains controversy, and local data is also scarce. Therefore, this study was planned to further explore the use of probiotics to furnish the local data. If significantly less mean duration of diarrhea is noted in the probiotic group, it will help to add probiotic bacillus clausii in routine treatment regimen recommended by WHO and to decrease costs associated with prolonged treatment. However, if otherwise results will be noted it will help to rule out use of probiotic bacillus clausii in children with acute diarrhea to avoid its unnecessary use.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
184
Patients were given 2 billion spores of probiotic (Bacillus clausii) every12 hours, contained in a small bottle.
Children Hospital
Lahore, Punjab Province, Pakistan
Stool frequency
A frequency of defecation of \< 3 stools per day marked the effectiveness of the treatment.
Time frame: 5 days
Consistency of stools
The treatment was considered effective if the consistency of stools became semi-solid.
Time frame: 5 days
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