Biomarkers and Unstable Carotid Plaque

Fondazione Policlinico Universitario Agostino Gemelli IRCCS200 enrolled

Overview

This prospective study investigated associations between circulating miRNAs and symptomatic and asymptomatic ICAS, carotid plaque morphology and future cardiovascular events.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Carotid Artery Diseases

Interventions

Carotid endarterectomyPROCEDURE

Carotid endarterectomy, plaque histological analysis and miRNA expression

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Presence of significant internal carotid artery stenosis referred to carotid artery endarterectomy. * Age\>18 years Exclusion Criteria: * Presence of significant internal carotid artery stenosis referred to carotid artery stenting

Locations (1)

Fondazione Policlinico Universitario A. Gemelli IRCCS

Roma, RM, Italy

RECRUITING

Outcomes

Primary Outcomes

miRNA levels

miRNA levels and plaque vulnerability

Time frame: 30 days

Data from ClinicalTrials.gov

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