Hyperbaric Oxygen Therapy Combined With Polarized Light Therapy Effect on Neuropathic Foot Ulcer

Al-Zaytoonah University of Jordan40 enrolled

Overview

Neuropathic ulcers develop due to nerve damage (neuropathy), commonly seen in conditions like diabetes, leading to loss of sensation, repetitive trauma, and poor wound healing. These ulcers typically occur on weight-bearing areas, hyperbaric oxygen and polarized light therapies may have a synergistic effect, improving oxygenation, cellular activity, and overall healing outcomes in neuropathic ulcers, particularly in diabetic foot ulcers.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Neuropathic Diabetic Ulcer - Foot

Interventions

Hyperbaric oxygen therapy combined with polarized light therapyOTHER

Optimum regime of therapy increase healing rate of neuropathic foot ulcer is a challenge for researchers to save patient normal life

traditional treatmentOTHER

topical medication

Eligibility

Sex: ALLMin age: 55 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All patients had cardiac ejection fraction (CEF) 50% * blood pressure (BP) 150/90mmHg. * Chest X-ray was reported normal * all patients were clinically evaluated by a specialized ear, nose, and throat (ENT) physician to ensure suitability for the hyperbaric chamber. Exclusion Criteria: * chronic obstructive pulmonary disease, malignancy * cardiac pacemakers, or any disorder that lead to ulcers other than diabetes * chronic peripheral arterial disease.

Locations (1)

Modern University For Technology and Information

Cairo, Egypt

Outcomes

Primary Outcomes

Ulcer volume using Saline injection method

Time frame: 4 weeks

Secondary Outcomes

Tcpo2 at ulcer edge using Pulse Oximeter

Time frame: 4 weeks

Emg pre and at end (Sensory NCS (Sural nerve)

Time frame: 4 weeks

Data from ClinicalTrials.gov

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