Comparative Study Between Oxytocin Infusion Before and After Placental Delivery on Blood Loss During and After Cesarean Delivery .

Cairo University64 enrolled

Overview

Participants were randomized using computer-generated random numbers into 2 groups. Group I included 32 women who received oxytocin infusion before placental delivery just after cord clamping and group II included 32 women who received oxytocin infusion after placental delivery. In both groups 10 IU of oxytocin (Syntocinon, Novartis, Basel, Switzerland) were diluted in 500 mL of normal saline and administered through intravenous infusion over 30 minutes.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

Conditions

Intraoperative Blood Loss

Interventions

OxytocinDRUG

10 IU of oxytocin (Syntocinon, Novartis, Basel, Switzerland) were diluted in 500 mL of normal saline and administered through intravenous infusion over 30 minutes.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18 - 40 years * singleton full term pregnancy. * Candidate for elective cesarean delivery under spinal anaesthesia Exclusion Criteria: * women at high risk for intraoperative bleeding as those with placenta previa or other placental abnormalities * women with bleeding or coagulation disorders. * Medical disorder associating pregnancy as preeclampsia or diabetes * Allergy or contraindications to oxytocin * Fetal macrosomia, or congenital anomalies * Polyhydramnios * Uterine abnormalities as fibroids * Women with intraoperative complications as vascular or visceral injuries

Locations (1)

Armed force faculty of medicine

Cairo, Egypt

Outcomes

Primary Outcomes

Intraoperative blood loss

This was measured by weighing the surgical sponges and the suction canisters used during the procedure

Time frame: during cesarean delivery

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.