This study will assess the relative bioavailability of two different Oral formulations of tavapadon in healthy adult participants.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
83
Oral: Tablet
Acpru /Id# 275870
Grayslake, Illinois, United States
Number of Participants Experiencing Adverse Events
An adverse event is defined as any untoward medical occurrence in a patient or clinical investigation participant administered a pharmaceutical product and which does not necessarily have a causal relationship with this treatment
Time frame: Up to approximately 53 days
Maximum Observed Plasma Concentration (Cmax) of Tavapadon
(Cmax) of Tavapadon
Time frame: Up to approximately 22 days
Time to Cmax (Tmax) of Tavapadon
Tmax of Tavapadon
Time frame: Up to approximately 22 days
Apparent Terminal Phase Elimination Rate Constant (β) of Tavapadon
Apparent Terminal Phase Elimination Rate Constant (β) of Tavapadon
Time frame: Up to approximately 22 days
Terminal Phase Elimination Half-life (t1/2) of Tavapadon
Terminal Phase Elimination Half-life (t1/2) of Tavapadon
Time frame: Up to approximately 22 days
Area Under the Plasma Concentration-time Curve Over the Dosing Interval (AUCτ) of Tavapadon
Area Under the Plasma Concentration-time Curve Over the Dosing Interval (AUCτ) of Tavapadon
Time frame: Up to approximately 22 days
Area Under the Plasma Concentration-time Curve from Time Zero to Infinity (AUCinf) of Tavapadon
Area Under the Plasma Concentration-time Curve from Time Zero to Infinity (AUCinf) of Tavapadon
Time frame: Up to approximately 22 days
Trough Concentration (Ctrough) of Tavapadon
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Trough Concentration (Ctrough) of Tavapadon
Time frame: Up to approximately 22 days