The Association Mechanism Between the Microbiome and the Development of Community Pneumonia Was Studied Based on the Analysis of Pulmonary Microbiota - Host Interaction Network

N/AActive Not RecruitingNCT06896019

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University37 enrolled

Overview

1. The difference of lung flora between the healthy group and the CAP group was compared, and the core flora involved in the development of CAP was identified. 2. To predict the metabolites associated with CAP. 3. Identification of genes related to immune response in CAP. 4. Construct the pulmonary microbiota - host interaction network with metabolites as the link.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Community Pneumonia

Interventions

Community PneumoniaDIAGNOSTIC_TEST

The BALF of CAP patients

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * According to the CAP clinical diagnostic criteria in the Guidelines for the Diagnosis and Treatment of Community-Acquired Pneumonia in Adults in China (2016 edition), cases eligible for community-acquired pneumonia were included and screened. Exclusion Criteria: * Alveolar lavage fluid samples without electronic bronchoscopy were excluded for mNGS etiological examination of the case.

The Association Mechanism Between the Microbiome and the Development of Community Pneumonia Was Studied Based on the Analysis of Pulmonary Microbiota - Host Interaction Network

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes