The aim of this retrospective observational study was to describe the epidemiology of Neisseria gonorrhoeae septic arthritis over the last 10 years at Brest and Rennes university hospitals. The main question is whether there are any risk factors based on the epidemiological and clinical data on these cases. The second objective is to characterize the gonococcal strains isolated in order to determine whether there is a common clone, a virulence factor or specific resistance genes.
Study Type
OBSERVATIONAL
Enrollment
11
Rennes University Hospital
Rennes, Brittany Region, France
RECRUITINGCHU de BREST
Brest, France
RECRUITINGAge
years
Time frame: 10 years
Date of sampling
DD/MM/YYYY
Time frame: 10 years
Type of sample
joint fluid or joint fluid on blood culture bottle
Time frame: 10 years
Rate of white blood cells
quantification of white blood cells /mm3
Time frame: 10 years
Sexually transmitted infection
associated or not, if associated, name of STI and localization
Time frame: 10 years
Men who have sex with men
yes or no
Time frame: 10 years
HIV pre-exposure prophylaxis (PreP)
yes or no
Time frame: 10 years
Comorbidities
any history mentioned in the medical file, such as fracture, illness, treatment, chronic alcoholism, cancer, diabetes, etc.
Time frame: 10 years
Imaging
medical conclusion of the ultrasound or radiology performed
Time frame: 10 years
Blood cultures (peripheral blood)
positive or negative
Time frame: 10 years
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time to diagnosis
in days (between onset of symptoms and antibiotics)
Time frame: 10 years
Treatments implemented
name of the probabilistic treatment (antibiotic) and after identification or antibiogram
Time frame: 10 years
Antibiotic sensitivity profile
Susceptibility or resistance according to SIR methodology and, if achieved: minimum inhibitory concentrations of antibiotics tested on the strain in mg/L
Time frame: 10 years
Surgery
yes or not
Time frame: 10 years
Evolution
recovery or relapse
Time frame: 10 years
Rate of neutrophils
proportion of neutrophils in %.
Time frame: 10 years
Rate of CRP (C-reactive protein)
in mg/L
Time frame: 10 years
Molecular typing: clone
performed on strains sent to the Centre National de Référence des IST - APHP
Time frame: 10 years
Molecular typing: virulence factors
performed on strains sent to the Centre National de Référence des IST - APHP
Time frame: 10 years
Molecular typing: resistance genes
performed on strains sent to the Centre National de Référence des IST - APHP
Time frame: 10 years