WiSSPr is a prospective observational cohort study grounded in community-based participatory research principles with a community advisory board (CAB) of key population (KP) civil society organi sations (KP-CSOs) and the Ministry of Health (MoH).
WiSSPr is a prospective observational cohort study grounded in community-based participatory research principles with a community advisory board (CAB) of key population (KP) civil society organi sations (KP-CSOs) and the Ministry of Health (MoH). We will administer a one-time psychosocial survey vetted by the CAB and follow 300 WESW in the electronic medical record for three months to measure PrEP initiation (#/% ever taking PrEP) and persistence (immediate discontinuation and a medication possession ratio). We will conduct in-depth interviews with a purposive sample of 18 women, including 12 WESW and 6 peer navigators who support routine HIV screening and PrEP delivery, in two community hubs serving KPs since October 2021. We seek to value KP communities as equal contributors to the knowledge production process by actively engaging KP-CSOs throughout the research process. Expected outcomes include quantitative measures of PrEP initiation and persistence among WESW, and qualitative insights into the enablers and barriers to PrEP use informed by participants' lived experiences. https://doi.org/10.1136/bmjopen-2023-080218
Study Type
OBSERVATIONAL
Enrollment
299
oral PrEP
Centre for Infectious Disease Research Zambia
Lusaka, Zambia
PrEP initiation (#/% ever taken PrEP)
PrEP initiation (Number or percentage of Women Engaging in Sex Work (WESW) initiating on PrEP)
Time frame: 3 months
PrEP Persistence (#/ % eligible refills obtained until first discontinuation)
PrEP persistence. Number or percentage of women engaging in sex work with high levels of stigma who will persist on PrEP
Time frame: 3 months
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