The goal of this clinical trial is to learn if propolis administration works to change the level of Low Density Lipoprotein (LDL) and High Density Lipoprotein cholesterol (HDL) in diabetic type 2 patients. The main questions it aims to answer are: \- Is giving 1 drops/ 10kg/ times, twice daily for 8 weeks will change the level of LDL and HDL level in diabetic type 2 patients compared to placebo? Researchers will compare propolis to a placebo (a look-alike substance that contains no drug) to see if propolis works to change LDL and HDL cholesterol level. Participants will: * Take propolis or a placebo, 2 times daily with given dose (1 drops/10 kg/times) every day for 2 months * Visit the sub-district health centre once every 2 weeks for checkups * Get their blood checked before and after intervention
Subject allocation into groups will be made by third party to ensure masking/ blinding protocol. Data that will be taken from participants : * Private information * Medication history (for type 2 Diabetes Mellitus) * Food intake (calories, fats, carbohydrate, protein, and flavonoid intake) * Physical activity status
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
64
The intervention given is propolis drops that are approved by Indonesian Food and Drug Authority
The given placebo are look-alike substance with no effect
University of Indonesia Faculty of Biomedical Science
Jakarta, Indonesia
RECRUITINGLow Density Lipoprotein
LDL level will be measured twice, before and after intervention
Time frame: 8 weeks
High Density Lipoprotein
HDL will be measured twice, before and after intervention
Time frame: 8 weeks
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