The small intestine and feces of subjects undergoing endurance exercise will be sampled to examine their microbiome composition
The close relationship between humans and the commensal microbes of their gut microbiota represents vast potential for health maintenance, but most efforts have been focused on disease. Gastrointestinal (GI) problems are very common especially in endurance athletes, and are known to impair performance or subsequent recovery. Moreover, GI symptoms among athletes vary enormously, and some athletes are more prone than others; the links between this variation and the differences in microbiome composition across individuals have not been elucidated. The investigators propose to use a novel, non-invasive sampling technology to quantify the effects of exercise on the GI environment including the small intestines, and aim to establish the potential for dietary interventions to improve recovery from exercise.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
20
Participants perform moderate to strenuous exercise for up to 20 minutes on a treadmill after swallowing a microbiome sampling capsule.
Cooling gloves to prevent rise in core body temperature during exercise
Capsule used for collecting intestinal tract contents
Stanford University
Stanford, California, United States
RECRUITINGNumber of participants completing exercise
Target goal is 80% of subjects will complete their exercise testing
Time frame: 1 day
Volume of intestinal fluid from subjects for analysis
Target goal is 80% of subjects to have at least 100ul of intestinal fluid collected from microbiome-sampling capsule
Time frame: 2 weeks
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