APIXABAN App Study

Dong-Ju Choi40 enrolled

Overview

The aim of this clinical trial is to evaluate whether the medication reminder app and video call can improve medication adherence to apixaban in patients with AF and comorbidities. Patients with AF and comorbid heart disease taking apixaban who meet the inclusion criteria will be randomised 1:1 to a treatment arm using a medication reminder app and bi-weekly video education and a control arm using the medication reminder app alone to compare medication adherence. Patients in both groups will use the medication app, but only the treatment group will receive additional education and feedback via video call every two weeks to reinforce the use of the medication app and medication reminders with video education. The study aims to assess the change in adherence between the two groups at week 8.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Atrial Fibrillation

Interventions

Eligibility

Sex: ALLMin age: 19 Years

Medical Language ↔ Plain English

Participants must meet all of the following criteria: Adults aged 19 years or older with a diagnosis of atrial fibrillation (AF) Presence of at least one of the following cardiovascular or metabolic comorbidities: A. Heart failure B. Hypertension C. Coronary artery disease D. Peripheral arterial disease E. Diabetes mellitus F. Stroke G. Other cardiac diseases requiring treatment Currently taking or planning to initiate oral anticoagulation therapy with apixaban Able to use a smartphone with an Android operating system Voluntarily provided written informed consent to participate in the clinical trial after being adequately informed of its purpose, procedures, and potential risks 2\. Exclusion Criteria Participants will be excluded if any of the following conditions apply: Creatinine clearance (CCr) \< 15 mL/min Presence of moderate to severe mitral stenosis History of mitral valve repair or replacement Clinically significant history of alcohol or substance abuse Deemed by the investigator to be legally or psychologically unsuitable for participation in the clinical trial Participation in another clinical trial involving investigational drugs within 4 weeks prior to screening Declines or is unwilling to provide informed consent for participation in this study