The study is being conducted to evaluate the safety, tolerability, pharmacokinetics and preliminary efficacy of SHR-3792 injection monotherapy for patients with advanced solid tumors, and to explore the reasonable dosage of SHR-3792 injection monotherapy for patients with advanced solid tumors.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
150
SHR-3792 injection.
Shandong First Medical University Affiliated Cancer Hospital
Jinan, Shandong, China
RECRUITINGMaximum tolerated dose (MTD)
Time frame: From the first dose of study medication up to 21 days.
Recommended phase Ⅱ dose (RP2D)
Time frame: From the first dose of study medication up to 21 days.
Incidence of dose limited toxicity (DLT)
Time frame: From the first dose of study medication up to 21 days.
Adverse events (AEs)
Time frame: Up to 24 weeks.
Serious adverse events (SAEs)
Time frame: Up to 24 weeks.
Objective response rate (ORR)
Time frame: Up to 6 months.
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