Al18F-HER2-BCH PET in Breast Patients Treated With Neoadjuvant Therapy

Inclusion Criteria: 1. Aged ≥18 years old; ECOG 0 or 1; 2. Patients with newly diagnosis HER2 positive or suspicious positive tumors; 3. Receives neoadjuvant therapy 4. Has adequate cardiac, bone marrow, renal, hepatic and blood clotting functions; 5. Life expectancy \> 3 months - Exclusion Criteria: 1. Significant hepatic or renal dysfunction; 2. Is pregnant or ready to pregnant; 3. Cannot keep their states for half an hour; 4. Refused to join the clinical research; 5. Suffering from claustrophobia or other mental disorders; 6. Any other situation that researchers considered it unsuitable to participate in the trial.