Hepatic Doppler to Assess Venous Congestion During Invasive Mechanical Ventilation (DOHECOV)

University Hospital, Brest100 enrolled

Overview

The purpose of the study is to investigate venous congestion using hepatic vein doppler for ICU patients with invasive mechanical ventilastion. The primary outcome is the systolic to diastolic hepatic vein velocity ratio S/D . The objective is to find a significant association between S/D and different congestion indicators.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Congestion, Venous

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * intubated for more than 24 hours Exclusion Criteria: * Chronic end-stage renal disease on admission * Atrial Fibrillation * Cirrhosis * Portal thrombosis * Refusal to participate * non-opposition could not be obtained from themselves or their trusted support person in the event of incapacity * Under legal protection.

Locations (1)

Chu Brest

Brest, France

RECRUITING

Outcomes

Primary Outcomes

Systolic to diastolic hepatic vein velocity ratio S/D

Relate S/D ratio to clinical data on venous congestion: input/output balance, weight variation, renal insufficiency, diuresis, edema.

Time frame: 24 hours after intubation and after every 48 hours until extubation up to 12 weeks

Central Contacts

Gwenael PRAT, phD

CONTACT

0298347181 gwenael.prat@chu-brest.fr

Hamza CHRAIBI, phD

CONTACT

0298347181 hamza.chraibi@chu-brest.fr

Data from ClinicalTrials.gov

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