Comparison Between Interleukin 6 and Procalcitonin in Detecting Sepsis and Incidence of Mortality in Burn ICU Patients

Ain Shams University70 enrolled

Overview

The investigators will compare the efficacy of Interleukin-6 (IL-6) as a better indicator than procalcitonin in burn patients with sepsis or septic shock regarding success of treatment and early ICU discharge.

Interleukin 6 and procalcitonin will be sampled for all patients on days 1, 3, 7, and 10. Treatment plan will be initiated to all patients according to the burn ICU protocol. According to the lab results, interleukin 6 and procalcitonin will guide the investigators to take decisions regarding clinical improvement and ICU stay.

Study Type

INTERVENTIONAL

Allocation

Purpose

OTHER

Masking

NONE

Enrollment

Conditions

Burns Sepsis Septic Shock Death

Interventions

Interleukin 6DIAGNOSTIC_TEST

Interleukin 6 and procalcitonin will be sampled for all patients on days 1, 3, 7, and 10

Eligibility

Sex: ALLMin age: 25 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with acute burn admitted to burn ICU within 24 hours from the burn incidence. * patients with burn percentage of 25% to 50% of total body surface area * patients with second to third degree burns * ASA 1 and ASA 2 patients Exclusion Criteria: * Burn percentage more than 50% or less than 25% of total body surface area * Having autoimmune diseases * Cancer patients * ASA 3 and ASA 4 patients

Locations (1)

Ain Shams University

Cairo, Egypt

RECRUITING

Outcomes

Primary Outcomes

Occurrence of sepsis and septic shock

Prediction of occurrence of sepsis and septic shock

Time frame: From day 1 to day 10 in burn ICU

Secondary Outcomes

Length of ICU stay

Response to treatment and length of ICU stay for over one month

Time frame: One month after ICU admission

Central Contacts

Ahmed H Elsayed, M.B.B.CH

CONTACT

+201016305451 AhmedHanyAbdelfatah@med.asu.edu.eg

Data from ClinicalTrials.gov

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