The main purpose of this study is to compare the bioavailability of 3 different formulations of LY4100511 and if the use of a proton pump inhibitor (PPI) alters the bioavailability of the 3 different formulations.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
1
Administered orally.
Administered orally.
Clinical Pharmacology of Miami
Miami, Florida, United States
Alliance for Multispecialty Research, LLC
Knoxville, Tennessee, United States
Pharmacokinetic (PK): Area Under the Concentration Curve from 0 to Infinity (AUC0-∞) of LY4100511 (DC-853)
PK: AUC0-∞ of LY4100511
Time frame: Predose up to 26 Days
Pharmacokinetic (PK): Maximum Concentration (Cmax) of LY4100511 (DC-853)
PK: Cmax of LY4100511 (DC-853)
Time frame: Predose up to 26 Days
Pharmacokinetic (PK): Area Under the Concentration-Time Curve from Time 0 to the Time of the Last Quantifiable Concentration (AUC0-T) of LY4100511 (DC-853)
PK: AUC0-T of LY4100511 (DC-853)
Time frame: Predose up to 26 Days
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