This Present Study Can be Used by Clinicians Who Treat Psychiatric Patients: Dentists Might Expect Xerogenic Side Effects of Specific Psychiatric Drugs Which Can Affect Dental Treatment, and the Results Can Help Psychiatrist to Choose the Less Xerogenic Psychiatric Medication

N/ACompletedNCT06920472

Semmelweis University361 enrolled

Overview

The goal of this observational study is to learn about the effects of psychiatric drug therapies on intra- and extra-oral sicca symptoms and salivation. The main question that it aims to answer is: Does taking psychiatric medication cause oral dryness and/or any changes on whole and minor saliva secretion? Participants taking psychiatric medication answered a 16-question questionnare, and their saliva production was measured by Periotron device and by spitting method.

Study Type

OBSERVATIONAL

Enrollment

361

Conditions

Psychiatric Disorders Xerostomia Due to Hyposecretion of Salivary Gland

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: In the psychiatric group, the inclusion criteria was taking specific psychiatric medications. Exclusion Criteria: In the control group the exclusion criteria was reporting any diseases and taking medicines.

Outcomes

Primary Outcomes

Unstimulated whole saliva flow rate (UWS)

UWS was determined using the "spitting" method (Sreebny 2000). Whole saliva was collected for 5 minutes into a previously weighted empty cup, and then measured again after collecting the saliva. The results are in ml/min.

Minor salivary gland (MSG) secretions

Palatal and labial MSG flow rates were measured by the Periotron 8010® (Oraflow Inc. Amytiville, USA) device with filter paper discs. The results are transferred into µl/cm2/min.

Time frame: Through study completion, an average of 1 year