Comparison of Efficacy of Oral Fluconazole Versus Oral Itraconazole in the Treatment of Pityriasis Versicolor

Phase 4RecruitingNCT06922344

Khyber Teaching Hospital106 enrolled

Overview

This study compares the efficacy of two drugs, namely flucanazole and itraconazole for the treatment of a common fungal infection of skin.

Pityriasis versicolor is a common fungal infection of the superficial skin layers. Avalible treatment options include topical and systemic drugs. fluconazole and itraconazole are commonly used systemic agents. The aim of this study is to compare the efficacy of the two systemic drugs.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

106

Conditions

Pityriasis Versicolor

Interventions

FluconazoleDRUG

Oral fluconazole prescribed to group A

ItraconazoleDRUG

Oral itraconazole prescribed to Group B

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All cases of Pityriasis versicolor Exclusion Criteria: * Patients with history of chronic renal or liver disease, malignancy , or undergoing any kind of chemotherapy or radiotherapy or having cardiac conduction abnormalities. * Patients who received any anti-fungal therapy in the last one month. * Pregnant or lactating women.

Locations (1)

Khyber Teaching Hospital

Peshawar, KPK, Pakistan

RECRUITING

Outcomes

Primary Outcomes

Efficacy of Treatment

Efficacy of treatment is defined by absence of scaling by naked eye examination ,absence of yellow or golden scale reflection on woods lamp examination and absence of fungal hyphae on microscopic examination.

Time frame: Upto 8 weeks

Data from ClinicalTrials.gov

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