The objective of this trial is to assess the effects of a 7-day diet containing inulin vs. a control diet on energy expenditure in adults with overweight/obesity or normal weight.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
QUADRUPLE
Enrollment
61
Bar with inulin - high fiber
Bar without inulin - low fiber
Biofortis Clinical Research
Addison, Illinois, United States
Resting Energy Expenditure
Measured in kcal/day
Time frame: Measured on days 7 and 21 where days 1 and 15 are the first day of study product intake for each treatment. Day 7 to 14 is the washout period.
Diet Induced Thermogenesis
Assessed as the AUC and niAUC during the full test period
Time frame: Measured on days 7 and 21 where days 1 and 15 are the first day of study product intake for each treatment. Day 7 to 14 is the washout period.
Diet Induced Thermogenesis
Assessed as the AUC and niAUC during the breakfast period
Time frame: Measured on days 7 and 21 where days 1 and 15 are the first day of study product intake for each treatment. Day 7 to 14 is the washout period.
Diet Induced Thermogenesis
Assessed as the AUC and niAUC during the lunch period
Time frame: Measured on days 7 and 21 where days 1 and 15 are the first day of study product intake for each treatment. Day 7 to 14 is the washout period.
Postprandial carbohydrate oxidation rate
Assessed as the AUC and niAUC during the full test period
Time frame: Measured on days 7 and 21 where days 1 and 15 are the first day of study product intake for each treatment. Day 7 to 14 is the washout period.
Postprandial carbohydrate oxidation rate
Assessed as the AUC and niAUC during the breakfast period
Time frame: Measured on days 7 and 21 where days 1 and 15 are the first day of study product intake for each treatment. Day 7 to 14 is the washout period.
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Postprandial carbohydrate oxidation rate
Assessed as the AUC and niAUC during the lunch period
Time frame: Measured on days 7 and 21 where days 1 and 15 are the first day of study product intake for each treatment. Day 7 to 14 is the washout period.
Postprandial fat oxidation rate
Assessed as the AUC and niAUC during the full test period
Time frame: Measured on days 7 and 21 where days 1 and 15 are the first day of study product intake for each treatment. Day 7 to 14 is the washout period.
Postprandial fat oxidation rate
Assessed as the AUC and niAUC during the breakfast period
Time frame: Measured on days 7 and 21 where days 1 and 15 are the first day of study product intake for each treatment. Day 7 to 14 is the washout period.
Postprandial fat oxidation rate
Assessed as the AUC and niAUC during the lunch period
Time frame: Measured on days 7 and 21 where days 1 and 15 are the first day of study product intake for each treatment. Day 7 to 14 is the washout period.
Postprandial respiratory exchange ration (RER)
Assessed as the AUC and niAUC during the full test period
Time frame: Measured on days 7 and 21 where days 1 and 15 are the first day of study product intake for each treatment. Day 7 to 14 is the washout period.
Postprandial respiratory exchange ration (RER)
Assessed as the AUC and niAUC during the breakfast period
Time frame: Measured on days 7 and 21 where days 1 and 15 are the first day of study product intake for each treatment. Day 7 to 14 is the washout period.
Postprandial respiratory exchange ration (RER)
Assessed as the AUC and niAUC during the lunch period
Time frame: Measured on days 7 and 21 where days 1 and 15 are the first day of study product intake for each treatment. Day 7 to 14 is the washout period.
Fasting Carbohydrate Oxidation
Assessed from pre-consumption
Time frame: pre-consumption
Fasting Fat Oxidation
Assessed from pre-consumption
Time frame: pre-consumption
Fasting RER
Assessed from pre-consumption
Time frame: pre-consumption
Fat Mass
Measured using the Styku body scanner.
Time frame: Measured on days 7 and 21 where days 1 and 15 are the first day of study product intake for each treatment. Day 7 to 14 is the washout period.
Fat-Free Mass
Calculated by subtracting fat mass from body mass.
Time frame: Measured on days 7 and 21 where days 1 and 15 are the first day of study product intake for each treatment. Day 7 to 14 is the washout period.