The anesthesia and surgical procedures from the time the patient enters the operating room to discharge from the recovery room are identical to those used in conventional airway surgeries performed under general anesthesia with Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE). The time point at which rescue ventilation is required due to a drop in oxygen saturation below 92% during anesthesia will be recorded, and the predictive factors for this event will be investigated.
Study Type
OBSERVATIONAL
Enrollment
80
Time to Rescue Ventilation Due to Hypoxemia During Airway Surgery With THRIVE Under General Anesthesia
The primary outcome is the time from the start of apnea to the initiation of rescue ventilation, defined as the point when oxygen saturation (SpO₂) falls to 92% or below during airway surgery under general anesthesia with Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE). This will be measured using continuously recorded intraoperative data. The aim is to identify clinical predictors (e.g., anatomical and physiological variables) associated with the need for rescue ventilation.
Time frame: From the start of apnea to the initiation of rescue ventilation during surgery (intraoperative period)
Lowest Oxygen Saturation After Initiation of Rescue Ventilation
This outcome measures the lowest oxygen saturation (SpO₂) observed after the initiation of rescue ventilation during airway surgery with THRIVE under general anesthesia. Data will be extracted from intraoperative monitoring records.
Time frame: From the start of apnea to the initiation of rescue ventilation during surgery (intraoperative period)
Time to Recovery of SpO₂ to 100% After Rescue Ventilation
This outcome measures the time interval from the start of rescue ventilation to the recovery of oxygen saturation (SpO₂) to 100%. The measurement will help evaluate the efficacy of rescue ventilation in restoring oxygenation.
Time frame: From the start of apnea to the initiation of rescue ventilation during surgery (intraoperative period)
End-Tidal CO₂ at the Time of Rescue Ventilation
This outcome records the end-tidal carbon dioxide (EtCO₂) level at the moment rescue ventilation is initiated. It aims to assess the extent of CO₂ retention during apnea and its relationship to the timing of rescue ventilation.
Time frame: From the start of apnea to the initiation of rescue ventilation during surgery (intraoperative period)
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Predictive Factors for the Requirement of Rescue Ventilation
This outcome involves analysis of patient anatomical and physiological factors (e.g., Mallampati class, thyromental distance, neck circumference, presence of retrognathia) to determine their association with the need for rescue ventilation during THRIVE-supported airway surgery.
Time frame: From the start of apnea to the initiation of rescue ventilation during surgery (intraoperative period)