The purpose of this study is to assess how fast BGM0504 gets into the blood stream and how long it takes the body to remove it in participants with impaired kidney function compared to healthy participants.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
34
The First Affiliated Hospital of Shandong First Medical University (Qianfoshan Hospital, Shandong Province)
Jinan, Shandong, China
Area Under the Concentration Versus Time Curve (AUC) of BGM0504 From Time Zero to Tlast (AUC0-t)
Area Under the Concentration Versus Time Curve (AUC) of BGM0504 From Time Zero to Tlast (AUC0-t)
Time frame: Start of Treatment up to Day 29
Maximum Concentration of BGM0504 (Cmax)
Maximum Concentration of BGM0504 (Cmax)
Time frame: Start of Treatment up to Day 29
Area Under the Concentration Versus Time Curve (AUC) of BGM0504 From Time Zero to Infinity (AUC0-inf)
Area Under the Concentration Versus Time Curve (AUC) of BGM0504 From Time Zero to Infinity (AUC0-inf)
Time frame: Start of Treatment up to Day 29
Time to maximum concentration (Tmax)
Time to maximum concentration (Tmax)
Time frame: Start of Treatment up to Day 29
Apparent terminal half-life (t1/2)
Apparent terminal half-life (t1/2)
Time frame: Start of Treatment up to Day 29
Apparent clearance (CL/F)
Apparent clearance (CL/F)
Time frame: Start of Treatment up to Day 29
Incidence and severity of adverse events
Incidence and severity of adverse events
Time frame: Screening period up to Day 29
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Receive a single dose of BGM0504 injection