This study will investigate the acceptability and efficacy of 12 weeks of: Smart-device app-based (MyZone) Asynchronous Virtual, Synchronous Virtual, and in-person aerobic training in individuals at risk for Cardiovascular Disease (CVD) who do are not meeting American Heart Association (AHA) guidelines for physical activity. The study aims to 1) Assess the effect of several approaches to remote aerobic training on measures of physical activity, cardiovascular fitness and CVD risk, and 2) Quantitatively and qualitatively evaluate exercise training program fidelity, implementation, effectiveness, and remaining barriers to acceptance. Participants will be asked to undergo Cardiopulmonary Exercise Testing (CPET) before and after 12-weeks of training via one of the 4 modalities (random assignment) listed above. They will respond to questions regarding acceptability of the interventions.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
30
Gold-standard, facility-based sessions (3 sessions/week) with an onsite trainer guidance with an exercise Intensity of 40-80% heart rate reserve (HRR) or Rate of Perceived Exertion (RPE) 12-16.
Live-streamed exercise classes (3 sessions/week) with a trainer providing real-time feedback.
Participants exercise independently and follow a weekly progression plan (3-5 sessions/week (depending on the specific progression)).
Training using the Myzone platform, with participants wearing the Myzone heart rate monitor and using the Myzone app to receive real-time feedback and guidance during exercise sessions (3 days per week). Myzone integrates with its proprietary wearable devices to monitor heart rate and other activity metrics, providing real-time data to users via the app.
Participants will wear a Bluetooth-compatible heart rate monitor (e.g., apple watch/fitbit) that syncs with MapMyFitness. MapMyFitness automatically records workout sessions (duration, distance, heart rate, calories burned, and elevation gain where applicable).
Centralized telemetry monitors heart rates and provides immediate feedback for trainers to adjust exercise intensity.
Wearable device (chest strap or armband) that monitors heart rate.
NYU Langone Health
New York, New York, United States
RECRUITINGAverage minutes of moderate to vigorous physical activity per week
Outcome is measured via wearable technology (smart device).
Time frame: Up to 13 weeks
Change in peak oxygen consumption (VO2peak)
Peak oxygen consumption (VO2peak) is measured as the highest VO2 recorded during the course of a Cardiopulmonary Exercise Testing (CPET).
Time frame: Baseline, Week 13
Change in blood pressure
Time frame: Baseline, Week 13
Change in Body mass index (BMI)
BMI (kg/m2) will be calculated using measured body weight and height
Time frame: Baseline, Week 13
Change in body fat percentage
Body fat percentage will be assessed via multi-frequency bioelectrical impedance analysis (BIA) with 8 tactile electrodes.
Time frame: Baseline, Week 13
Change in fasting glucose levels
Time frame: Baseline, Week 13
Change in 36-Item Short Form Survey Instrument (SF-36)
SF-36 captures mental health, general health perception, emotional, and social role functioning. The SF-36 consists of eight scaled scores, which are the weighted sums of the questions in their section. Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. Higher scores indicate a more favorable health state.
Time frame: Baseline, Week 13
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