RCT of Mind-body in Long COVID and Myalgic Encephalomyelitis

Inclusion Criteria: * Age 18 years or older; * Individuals diagnosed with ME/CFS, according to the Institute of Medicine (2015) criteria, for more than six months. Exclusion Criteria: Individuals who: 1) are too ill to participate; 2) lack reliable internet; 3) cannot communicate in English; 4) Presently have or ever had inflammatory bowel disease; and/or 5) Have been prescribed or used an oral or systemic (infusion) antibiotic in the past one month-;; 6) are participating in a concurrent study; 7) are participating in a concurrent mind-body intervention during the study period including * Art Therapy * Autogenic training * Biofeedback/neurofeedback * Breathing exercise * Cognitive restructuring * Dynamic Neural Retraining System * Emotional Freedom Techniques (EFT) * Eye movement desensitization and reprocessing (EMDR) * Guided imagery * Hypnotherapy/self-hypnosis * Meditation (mindfulness, mantra, guided, transcendental) * Mindfulness-based cognitive therapy (MBCT) * Mindfulness-based Stress Reduction (MBSR) * Music therapy * Neurolinguistic programming * Psychological flexibility * Qigong * Relaxation therapy (relaxation response, progressive muscle relaxation) * Tai Chi * Visualization * Yoga and/or starting any other new treatment during the study period, including any mind-body therapy, psychotherapy, prescription medication, over-the-counter medication, etc; 8) have any active medical condition (untreated/uncontrolled) that may explain the presence of fatigue including: * untreated hypothyroidism (including Hashimoto's disease) * hyperthyroidism * diabetes mellitus * iron deficiency anemia * other treatable anemia * iron overload syndrome * adrenal insufficiency * Cushing's syndrome * anorexia nervosa * iatrogenic conditions such as side effects or interactions of medication(s) or supplements • Rheumatological disorders: * rheumatoid arthritis * lupus * polymyositis * polymyalgia rheumatica * Sjogren's Syndrome * Ehlers Danlos Syndromes \[Hypermobility type\] • Other heritable disorders of connective tissue: * Marfan syndrome * Stickler syndrome etc. * Multiple sclerosis * Celiac disease * Note: Patients with celiac disease can present without gastrointestinal symptoms • Immune disorders * such as HIV/AIDS • Sleep disorders * including obstructive sleep apnea • Prior illnesses may relapse or may not have completely resolved during treatment. * Examples are certain malignancies * leukemia * infectious diseases such as tuberculosis and chronic hepatitis • Active primary psychiatric disorders * eating disorders * alcohol * substance use disorder