The purpose of this study is to evaluate the efficacy and safety of Tafamidis Meglumine Soft Capsules in the Treatment of Adult Patients with Transthyretin Amyloid Polyneuropathy
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
15
20 mg orally once daily for 72 weeks
Qilu Hospital of Shandong University
Jinan, China
RECRUITINGChange from Baseline Neuropathy Impairment Score-Lower Limb (NIS-LL) at Week 72
Change from Baseline Neuropathy Impairment Score-Lower Limb (NIS-LL) at Week 72
Time frame: Baseline to 72 Weeks
Change from Baseline NIS-LL at Week 24 and Week 48
Change from Baseline NIS-LL at Week 24 and Week 48
Time frame: Baseline to 24 and 48 Weeks
Change from Baseline Modified Body Mass Index(mBMI) at Week 4, Week 8, Week 12,Week 24, Week 36,Week 48 and Week 72
Change from Baseline Modified Body Mass Index(mBMI) at Week 4, Week 8, Week 12,Week 24, Week 36,Week 48 and Week 72
Time frame: Baseline to 4, 8, 12, 24, 36, 48 and 72 Weeks
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