Virtuoso Improving Anatomic Bladder Lesion Excision (VIABLE) Trial

Inclusion Criteria: 1. The subject is 22 years or older. 2. The subject is eligible and fit for transurethral bladder lesion removal and/or biopsy and has an appropriate indication to go through this surgery. 3. The subject is willing and able to provide written informed consent and comply with the study protocol. 4. The subject can undergo general anesthesia per anesthesiologist assessment. 5. The subject's planned aggregated bladder lesion(s) excision specimens are smaller than 3 cm. Exclusion Criteria: 1. The subject has acute untreated urinary tract infection or urosepsis. 2. The subject has a documented nickel allergy or nickel sensitivity. 3. The subject is confirmed to be or suspected to be pregnant. 4. The subject is receiving anticoagulants and is unable or not willing to cease the medication for the investigational procedure. 5. The subject belongs to a vulnerable group (prisoner, etc.) 6. The subject has a urethral abnormality, implant, or previous surgery which would conflict with the procedure. 7. The subject has undergone a transurethral bladder resection procedure in the past 6 months. 8. The subject has a history of radiation treatment within the pelvis. 9. Bladder tumor base maximal dimension is greater than 3 cm. 10. Bladder tumor detected during intravesical therapy. 11. Previous histological diagnosis different than non-muscle invasive bladder cancer. 12. Presence or prior history of upper urinary tract malignancy. 13. Eastern Cooperative Oncology Group performance status greater than or equal to 3. 14. American Society of Anesthesiologists physical status classification of IV or above. 15. History of bleeding disorder, coagulation abnormality, or use of anticoagulants. 16. The presence of other active malignancy. 17. Life expectancy \<1 yr.