Neurocognitive Predictors of Health Risk Behaviors

N/AActive Not RecruitingNCT06941181

Virginia Polytechnic Institute and State University117 enrolled

Overview

This study proposes to extend the ongoing longitudinal study of health risk behaviors and obtain new data from former adolescents (followed previously from ages 13-22; Times 1-8) now from ages 23 to 28 (Times 9-11). The goal of this study is to examine the contribution of developing neurocognitive markers to substance use in young adulthood by following a well-characterized longitudinal sample.

The main questions it aims to answer is: what are the long-term effects of valuation and control decision-making systems on health risk behaviors? Participants will complete online surveys assessing their substance use behaviors and perform neurocognitive tasks related to risk processing and cognitive control across three time points.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

117

Conditions

Substance Use

Interventions

neurocognitive tasksOTHER

1. risk-processing: Participants choose between two choices across 72 trials of a forced choice decision-making neurocognitive task (Holt and Laury, 2002). Each trial included a high and low monetary outcome with an associated probability of occurring. Each choice option is shown as a pie with ten slices represented probabilities, in which each piece corresponded to ten percent. 2. cognitive control: A multi-source interference task (MSIT; Bush et al., 2003) is used in which participants are presented with three digits and asked to identify the digit different from the others. In the neutral condition, the target's identity is congruent with its relative position. In the interference condition, the target's identity does not match its relative position. There are a total of 96 neutral trials and 96 interference trials.

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: \- Adolescents (now young adults) who participated in the original longitudinal project. Exclusion Criteria: * standard contraindications for magnetic resonance imaging at the study onset * history of seizures/stroke * a head injury with \> 10 min of unconsciousness or neurological sequelae

Locations (2)

Virginia Tech

Blacksburg, Virginia, United States

Fralin Biomedical Research Institute at VTC

Roanoke, Virginia, United States

Outcomes

Primary Outcomes

substance use behaviors

Frequency (past year and past month use) of cigarette/tobacco, alcohol, cannabis, and other drug use will be asked.

Time frame: Approximately every 18 months, 3 times across 5 years

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.