ADRIATIC study explored the benefits of immune maintenance therapy after LS-SCLC radiotherapy and chemotherapy. In the presence of immunotherapy, is it necessary to increase the dosage of radiotherapy and can it further improve the efficacy? This study aims to explore the efficacy and safety of simultaneous integrated boost hyperfractionation radiotherapy combined with probiotics and Adalberg monoclonal antibody consolidation therapy for small cell lung cancer.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
60
Subjects received probiotics before radiotherapy
Increase radiation dose on the basis of conventional radiotherapy
Adebrelimab, 1200mg,q3w,2 year
Fudan University Shanghai Cancer Center
Shanghai, Shanghai Municipality, China
RECRUITINGone year progression free survival rate
Time frame: one year
Complete response rate at the end of radiotherapy for one month
Time frame: at the end of radiotherapy for one month
One year overall survival rate
Time frame: one year
one year Survival rate without distant metastasis
Time frame: one year
Adverse reactions
Time frame: one year
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.