Comparing Effectiveness of Steroids and Methotrexate in Treatment of Chronic Inflammatory Breast Disease

Inclusion Criteria: * Women, aged between 21 and 60 years * Positive diagnosis of idiopathic granulomatous mastitis based on histopathology results * Willing and able to give informed consent Exclusion Criteria (Patients who meet any of the following prerequisites will not be allowed to take part in this study): * Women who are currently pregnant or breastfeeding * Cognitive impairment which prevents the patient from giving voluntary consent * History of any psychiatric conditions such as depression, psychosis, schizophrenia etc. * History of cancer in the past 5 years * History of abnormal renal or liver function * History of diabetes mellitus * History of pulmonary lung disease, pneumonitis, or related conditions * Hepatitis B and/or Hepatitis C carrier * Diagnosed with tuberculosis (Positive microbiological evaluation for Grocott Methenamine Silver stain and Ziehl- Neelsen stain) * Any immunosuppressants or anti-inflammatory medications such as NSAIDS for the past 3 months * Concomitant medication that may have contraindication with prednisolone and methotrexate use * Hypersensitivity to components or drug products of prednisolone and methotrexate * Vaccination with live virus vaccines prior to or during treatment