Taking patients with locally advanced gastric adenocarcinoma (cT2-4a, N-/+, M0) as the research subjects, to evaluate whether the clinical efficacy of laparoscopic beyond D2 regional lymph node dissection for gastric cancer with indocyanine green tracer is better or not.
Study Type
OBSERVATIONAL
Enrollment
760
dissect the lymph nodes outside the extent of D2 LN region.
Fujian Medical University Union Hospital
Fuzhou, Fujian, China
RECRUITING3-year disease free survival rate
Disease-free survival is calculated from the day of surgery to the day of recurrence or death
Time frame: 3 years
Total number of retrieved lymph nodes
Total number of retrieved lymph nodes
Time frame: 30 days
Noncompliance rate of lymph node dissection
The LN dissection rate was determined by the number of patients in whom a LN station was harvested divided by the total number of patients who required retrieval at the corresponding LN station. Within the scope of D2 dissection, LN noncompliance was defined as the absence of LNs that should have been resected from \> 1 LN station.
Time frame: 30 days
Relationship between fluorescent lymph nodes in group A and total number of lymph nodes in group A
Relationship between the number of fluorescent lymph nodes in group A and total number of lymph nodes in group A
Time frame: 30 days
Relationship between fluorescent lymph nodes in Group A and positive lymph nodes in Group A (positive rate)
The number of positive lymph nodes in fluorescent lymph nodes is divided by the number of total fluorescent lymph nodes in Group A (True positive rate).
Time frame: 30 days
Relationship between fluorescent lymph nodes in Group A and negative lymph nodes in Group A (false positive rate)
The number of negative lymph nodes in fluorescent lymph nodes is divided by the number of total fluorescent lymph nodes in Group A (false positive rate).
Time frame: 30 days
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Relationship between non-fluorescent lymph nodes in Group A and negative lymph nodes in group A (negative rate)
The number of negative lymph nodes in not fluorescent lymph nodes is divided by the number of total not fluorescent lymph nodes in group A (True negative rate).
Time frame: 30 days
Relationship between nonfluorescent lymph nodes in Group A and positive lymph nodes in Group A (false negative rate)
The number of positive lymph nodes in not fluorescent lymph nodes is divided by the number of total not fluorescent lymph nodes in Group A (false negative rate).
Time frame: 30 days
Relationship between fluorescent lymph nodes in group B and total number of lymph nodes in group B
Relationship between the number of fluorescent lymph nodes in group B and total number of lymph nodes in group B
Time frame: 30 days
Relationship between fluorescent lymph nodes in Group B and positive lymph nodes in Group B (positive rate)
The number of positive lymph nodes in fluorescent lymph nodes is divided by the number of total fluorescent lymph nodes in Group B (True positive rate).
Time frame: 30 days
Relationship between fluorescent lymph nodes in Group B and negative lymph nodes in Group B (false positive rate)
The number of negative lymph nodes in fluorescent lymph nodes is divided by the number of total fluorescent lymph nodes in Group A (false positive rate).
Time frame: 30 days
Relationship between non-fluorescent lymph nodes in Group B and negative lymph nodes in group B (negative rate)
The number of negative lymph nodes in not fluorescent lymph nodes is divided by the number of total not fluorescent lymph nodes in group B (True negative rate).
Time frame: 30 days
Relationship between nonfluorescent lymph nodes in Group B and positive lymph nodes in Group B (false negative rate)
The number of positive lymph nodes in not fluorescent lymph nodes is divided by the number of total not fluorescent lymph nodes in Group B (false negative rate).
Time frame: 30 days
Number of metastatic lymph nodes
Number of metastatic lymph nodes
Time frame: 30 days
Metastasis rate of lymph nodes
Metastasis rate of lymph nodes
Time frame: 30 days
Postoperative complications
Postoperative complications were evaluated within 30 days following surgery. These postoperative complications include gastrointestinal-related complications, incision-related complications, respiratory complications, cardiovascular and cerebrovascular complications, urinary system complications, infection complications, embolism complications, and other complications. The grading of postoperative complications adopts the Clavien-Dindo classification.
Time frame: 30 days
Mortality rates
Patient died during hospitalization.
Time frame: 30 days
3-year overall survival rate
3-year overall survival rate
Time frame: 3 years
3-year recurrence pattern
3-year recurrence pattern
Time frame: 3 years
Postoperative recovery course
Time to first flatus after surgery, time to first ambulation after surgery, time to first liquid diet after surgery, time to first semi-liquid diet after surgery, length of hospital stay after surgery.
Time frame: 30 days
The incidence of intraoperative complications
Intraoperative complications were defined as bleeding due to named vessel injury, injury to visceral organs, mechanical factor-related problems, cardiopulmonary dysfunction due to hypercapnia, and other complications
Time frame: 30 days
Inflammatory and immune response
the values of hemoglobin, prealbumin, albumin, C-reactive protein, and white blood cell count from peripheral blood before the operation and on postoperative day 1, 3, 5 are recorded.
Time frame: 7 days