Hemogram Parameter Changes With Sepsis Filter

Samsun University92 enrolled

Overview

Hemodiafiltration is initiated in hemodynamically unstable patients in intensive care units. In some patients, additional devices called cytokine filters or sepsis filters are added to remove inflammatory cytokines. Data obtained from hemograms, such as platelet lymphocytosis ratio, are used in the diagnosis or prognosis of many diseases. This study focuses on the change in hemogram rates in patients who received hemofiltration and sepsis filters.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Platelet Abnormality Renal Failure Immune System Disorder

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Data of patients who were monitored in the Intensive Care between January 2020 and December 2022 and who were applied sepsis filters Exclusion Criteria: * -Patients who underwent hemodiafiltration with sepsis filter but could not be followed for 72 hours (death, etc.)

Locations (1)

Istinye University

Istanbul, Turkey (Türkiye)

Outcomes

Primary Outcomes

Platelet lymphocyte ratio change

Change in platelet lymphocyte ratio measured from hemogram at the beginning (day 0) and the ratio calculated from the sample taken on day 3 in patients undergoing hemodiafiltration with sepsis filter

Time frame: up to 72 hours

Secondary Outcomes

change in the other ratios derived from complete blood cell count

Changes in hemogram derivation ratios measured from the hemogram at the beginning (day 0) and the ratio calculated from the sample taken on day 3 in patients who underwent hemodiafiltration with sepsis filter

Time frame: up to 72 hours

Data from ClinicalTrials.gov

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