This is a prospective cohort study designed to assess intra-abdominal blood volume and hemodynamic status by measuring the diameter of the inferior vena cava (IVC) using 3D and Doppler ultrasound within 24 hours after gynecological surgery. The study will examine the association between these ultrasound findings and postoperative outcomes, including hemoglobin drop, need for blood transfusion, pain, infection, and length of hospitalization. Approximately 250 women undergoing laparotomy, laparoscopy, or vaginal surgery at Holy Family Hospital will be enrolled. The study also aimed to define postoperative normograms for fluid volume and IVC parameters and to evaluate whether ultrasound-guided decision-making could improve postoperative care and reduce unnecessary interventions.
Postoperative intra-abdominal bleeding is a significant contributor to morbidity and, in some cases, mortality following gynecological surgery. Timely recognition of intra-abdominal blood loss is essential for appropriate clinical intervention. In cases where bleeding is into the abdominal cavity, diagnosis is more difficult and may be delayed. Ultrasound is a non-invasive, rapid, and widely available tool for assessing free intra-abdominal and pelvic fluid. Modern machines allow for 3D volumetric assessment of fluid collections, as well as Doppler-based measurements of the inferior vena cava (IVC) diameter and its collapsibility index-both of which are known to correlate with intravascular volume status and blood loss. Currently, there are limited data establishing normal ranges of intra-abdominal fluid or IVC diameter postoperatively, and little is known about the magnitude of these measurements and clinical outcomes after gynecologic procedures. This prospective cohort study aims to quantify intra-abdominal fluid and determine IVC diameter and its collapsibility index using advanced ultrasound imaging within 24 hours after surgery. Patients undergoing open, laparoscopic, or vaginal gynecological procedures will be included. The study will explore correlations between ultrasound findings and clinical outcomes such as hemoglobin drop, need for blood transfusion, infection, pain, and length of hospital stay. Additionally, we aim to develop reference normograms for postoperative normal ranges of intraabdominal fluid volume and IVC diameter.
Study Type
OBSERVATIONAL
Enrollment
250
Transabdominal and transvaginal imaging will be performed to eligible women following gynecological surgery within 24 - 48 hours.
Holy Family hospital, Nazareth
Nazareth, Israel
RECRUITINGIncidence of intra-abdominal free fluid
Detection of any intra-abdominal or pelvic free fluid via ultrasound examination within 24 - 48 hours after gynecological surgery.
Time frame: Within 24-48 hours after surgery
Volume of intra-abdominal fluid
Measured in mL using 3D ultrasound
Time frame: Within 24-48 hours after surgery
Presence and size of pelvic hematoma
Using ultrasound to identify hematomas and measure their volume
Time frame: Within 24-48 hours after surgery
Inferior vena cava (IVC) diameter and collapsibility index
Using ultrasound Doppler to measure Inferior vena cava (IVC) diameter and collapsibility index
Time frame: Within 24-48 hours after surgery
Hemoglobin drop
Delta hemoglobin level before surgery and at 48-72 hours postoperatively.
Time frame: Within 24-48 hours after surgery
Need for blood transfusion
Number of packed red blood cells administered during hospitalization.
Time frame: Within 72 hours after surgery
Length of hospital stay
Total duration of hospitalization in days.
Time frame: Day 1 to day 7 after operation
Surgical site infection
Recording any infection in the part of the body where a surgery took place
Time frame: Within 96 hours after surgery
Postoperative fever
Body temperature ≥38.0°C within 72 hours after surgery.
Time frame: Within 96 hours after surgery
Patient discomfort from the ultrasound examination
Measured on a scale of 1 to 5 (1 = no discomfort, 5 = very uncomfortable).
Time frame: Immediately after ultrasound examination
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