Establishment of a Clinical and Prognostic Follow-up Cohort of Migraine Patients With Patent Foramen Ovale

Peking University Third Hospital330 enrolled

Overview

To establish a headache center in China that combines clinical, imaging and laboratory examinations, explore the feasible treatment options for migraine combined with patent foramen ovale, and search for the possible influencing factors, construct models that influence prognosis.

Study Type

OBSERVATIONAL

Enrollment

330

Conditions

Migraine Patent Foramen Ovale

Interventions

Conservative treatmentDRUG

Receive no antipaletet drug treatment and surgery

Antipaletet drugDRUG

Use of antipaletet drugs.

Patent Foramen Ovale ClosurePROCEDURE

Receive the surgery of Patent Foramen Ovale

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Meet the diagnostic criteria for migraine in the International Classification of Headache (ICHD-3); * Confirmation of patent foramen ovale through transthoracic echocardiography(TTE) or transesophageal echocardiography(TEE)/right heart contrast echocardiography * Agree to participate in the study and sign the informed consent form. Exclusion Criteria: * Can not sign the informed consent form or cooperate with follow-up.

Locations (1)

Peking University Third Hospital

Beijing, China

RECRUITING

Outcomes

Primary Outcomes

The changes of migraine attacks

Migraine attacks are an important indicator of improvement in symptoms. The comparison measures included headache frequency, duration, pain degree, VAS scores, HIT-6 scores, HAMA, HAMD, and PSQI.

Time frame: 3 months, 6 months, 1 year, 2 years and 3 years

Central Contacts

Yu Fu

CONTACT

13671185050 lilac_fu@126.com

Data from ClinicalTrials.gov

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