Arginine Plaque Metabolism Pilot Clinical Study

Inclusion Criteria: * Signed Informed Consent Form. * Male and female subjects aged 18-70 years, inclusive. * Availability for the nine-week duration of the clinical research study. * Good general health based on the opinion of the study investigator * Good general health Exclusion Criteria: * Moderate and/or advanced periodontal disease, rampant caries, or any condition that the dental examiner considers exclusionary from the study. * Five or more carious lesions requiring immediate care. * Concurrent participation in any other oral care clinical study or test panel. * Self-reported pregnant or lactating women. * Dental prophylaxis received in the past four weeks prior to baseline examinations * History of tobacco use-smoking, vaping and chewing tobacco * Presence of orthodontic bands, presence of partial removable dentures * Tumor(s) of the soft or hard tissues of the oral cavity * Use of antibiotics or stain inducing medications any time during the two month prior to entry into the study * Use of oral care products containing antimicrobials (Zn, Sn, CPC, triclosan, alcohol containing mouthwash, etc