This is a prospective observational study. To investigate the effect of serum calcium levels on postoperative pain in patients undergoing abdominal surgery, and to determine whether changes in serum calcium levels are a risk factor for postoperative pain.
This study aimed to measure the total serum calcium and ionized calcium levels both before and after surgery. Additionally, NRS scores were recorded at different time points.
Study Type
OBSERVATIONAL
Enrollment
350
Peripheral venous blood was collected before and after the surgery to measure the total serum calcium levels.
Arterial blood was collected before anesthesia induction and after removal of the artificial airway to measure ionized calcium levels.
The Second Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, China
RECRUITINGThe incidence of pain NRS score ≥6 within 48 hours after surgery
NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively）
Time frame: From the end of the surgery to 48 hours after surgery
The maximum incisional pain score at 0-12h postoperatively
NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively）
Time frame: From the end of the surgery to 12 hours after surgery
The maximum incisional pain score at 12-24h postoperatively
NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively）
Time frame: From 12hours to 24 hours after surgery
The maximum incisional pain score at 24-48h postoperatively
NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively）
Time frame: From 24 hours to 48 hours after surgery
The maximum visceral pain score at 0-12h postoperatively
NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively）
Time frame: From the end of the surgery to 12 hours after surgery
The maximum visceral pain score at 12-24h postoperatively
NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively）
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Time frame: From 12 hours to 24 hours after surgery
The maximum visceral pain score at 24-48h postoperatively
NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively）
Time frame: From 24 hours to 48 hours after surgery
Whether additional analgesia was administered within 48 hours after surgery
The proportion of patients who received additional analgesia out of the total patient group
Time frame: From the end of the surgery to 48 hours after surgery
Patient-controlled intravenous analgesia opioid consumption
PCIA opioid consumption was assessed by checking the PCIA electronic system
Time frame: From the end of the surgery to 24 hours and 48 hours after surgery