Azithromycin for Preventing Maternal and Neonatal Infections During Labor.

Phase 4Not Yet RecruitingNCT06958146

Armed Forces Hospital, Pakistan400 enrolled

Overview

In this study, we want to see the role of the antibiotic, azithromycin, in preventing maternal and neonatal infections, if the drug is given intrapartum to the mother

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

400

Conditions

Maternal and Neonatal Sepsis Intrapartum Antibiotics

Interventions

oral azithromycinDRUG

we will be administering single-dose oral azithromycin to ladies who go into labor and have no risk factors for sepsis, as there is increased risk of postpartum sepsis in both mother and neonate after normal vaginal delivery in low-income and middle-income countries

no azithromycinOTHER

participants in this arm will be given only standard labor care and no oral azithromycin

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * pregnant ladies with no risk factors for sepsis who go into spontaneous labor or induced labor Exclusion Criteria: * pregnant with risk factors for sepsis like maternal fever , raised WBC count, chorioamnionitis, or having. history of any adverse even with macrolides

Outcomes

Primary Outcomes

maternal infections

Time frame: birth to 6 weeks post partum

Secondary Outcomes

neonatal infections

Time frame: birth to 6 weeks post partum

Data from ClinicalTrials.gov

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