Assess the clinical efficacy of CSPR Toothpaste containing 8% arginine to provide dentinal hypersensitivity relief
The objective of this study is to assess the clinical efficacy of CSPR Toothpaste containing 8% arginine to provide dentinal hypersensitivity relief (tactile and air blast) at instant, 3 days, 4 weeks and 8 weeks in comparison to Colgate Cavity Protection Toothpaste over an eight-week period.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
100
a commercially available 8% arginine toothpaste
a commercially available fluoride toothpaste
West China Dental Institute of Chengdu
Chengdu, Sichuan, China
RECRUITINGTactile Sensitivity using the Yeaple Electronic Force Sensing Probe
Tactile sensitivity will be assessed by use of Sensing Probe Yeaple Electronic Force Sensing Probe, Model 200A. Sensitivity will be defined by a score in the range of 10-50 gms. of force.
Time frame: baseline, 3 day, 4 weeks, 8 weeks
Air Sensitivity using the Schiff Cold Air Sensitivity Scale
The air will be directed at the exposed buccal surface of the sensitive tooth air delivered by a standard dental unit syringe at a measured temperature of 19-21°C (70°F\[± 3°F\].
Time frame: baseline, 3 day, 4 weeks, 8 weeks
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