The main purpose of this study is to assess the ocular and systemic safety and tolerability of RO7669330 in participants with GA secondary to AMD in at least one eye in Part 1, or both eyes in Part 2, after multiple unilateral intravitreal (IVT) doses.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
27
RO7669330 will be administered as an IVT injection in the study eye per the schedule specified in the respective arms.
Syfovre™ will be administered as an IVT injection in the study eye per the schedule specified in the respective arms.
Izervay™ will be administered as an IVT injection in the study eye per the schedule specified in the respective arms.
Associated Retina Consultants - Phoenix - DocTrials - PPDS
Phoenix, Arizona, United States
Barnet Dulaney Perkins Eye Center
Sun City, Arizona, United States
Number of Participants With Adverse Events (AEs)
Time frame: Up to a maximum of 34 weeks
Number of Participants With Abnormalities Recorded in Standard Ophthalmological Assessments
The standard ophthalmological assessments that will be conducted may include the following: slit-lamp, indirect ophthalmology, intraocular pressure (IOP), best corrected visual acuity (BCVA), spectral domain optical coherence tomography (SD-OCT), fundus fluorescein angiography (FFA), and color fundus photography (CFP).
Time frame: Up to a maximum of 34 weeks
Part 1A and Part 2: Ocular and Systemic Concentration of RO7669330
Time frame: Up to a maximum of Week 24
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
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