Parkinson's disease (PD) is a neurological condition, which affects the brain. PD gets worse over time, but how quickly it progresses varies a lot from person to person. Some symptoms of PD are tremors, stiffness, and slowness of movement. This study will assess how effective Foslevodopa/Foscarbidopa is in treating Italian adult participants with advanced Parkinson disease under routine clinical practice. This study will also assess the caregiver quality of life (QOL) (if caregiver is present). Foslevodopa/Foscarbidopa is an approved drug for the treatment of Parkinson's Disease. Approximately 270 adult participants who are prescribed Foslevodopa/Foscarbidopa by their doctors will be enrolled across approximately 19 sites in Italy. Participants will receive Foslevodopa/Foscarbidopa subcutaneous infusion as prescribed by their physician. Participants will be followed for up to 12 months. There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.
Study Type
OBSERVATIONAL
Enrollment
270
IRCCS Oasi SS. Troina /ID# 273507
Troina, Enna, Italy
RECRUITINGIstituto Neurologico Mediterraneo Neuromed S.P.A. - Irccs /Id# 272695
Pozzilli, Isernia, Italy
RECRUITINGASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO /ID# 272949
Milan, Milano, Italy
RECRUITINGFondazione IRCCS Istituto Neurologico Carlo Besta /ID# 273225
Milan, Milano, Italy
RECRUITINGAzienda Ospedaliera Universitaria Luigi Vanvitelli /ID# 273434
Naples, Napoli, Italy
RECRUITINGA.O.U. CITTA' DELLA SALUTE E DELLA SCIENZA DI TORINO - Ospedale Molinette /ID# 273276
Turin, Piedmont, Italy
RECRUITINGAzienda Ospedaliera Universitaria Policlinico Tor Vergata /ID# 272834
Rome, Roma, Italy
RECRUITINGAzienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 273562
Rome, Roma, Italy
RECRUITINGFondazione Policlinico Universitario Agostino Gemelli IRCCS-Universita Cattolica /ID# 274539
Rome, Roma, Italy
RECRUITINGAzienda Ulss 3 Serenissima /ID# 273027
Venice, Venezia, Italy
RECRUITING...and 7 more locations
Change From Baseline in Quality of Life as Measured by PD Questionnaire-39 (PDQ-39) Summary Index
The PDQ-39 is a self-administered questionnaire which comprises 39 items addressing 8 domains of health in PD. These include: mobility, activities of daily living, emotional well-being, stigma, social support, cognition, communication, and bodily discomfort. The total score is between 0 and 156, calculated as the total sum of the items, and higher scores are associated with more severe symptoms. Negative changes from baseline indicate improvement.
Time frame: Up to approximately 6 months
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