This prospective multicenter observational study, conducted between June , 2022, and April, 2023, is a preplanned analysis of the AMESI study titled 'Demographics, diagnosis, management, and outcomes of non-occlusive mesenteric ischemia,' aiming primarily to describe the demographic profile, clinical presentation, and laboratory findings of patients with non-occlusive mesenteric ischemia (NOMI), and secondarily to identify independent risk factors as well as diagnostic approaches, management strategies, and outcomes-including in-hospital, 90-day, and one-year results.
Study Type
OBSERVATIONAL
Enrollment
566
No intervention, this is an observational study on patients with suspected acute mesenteric ischemia
University of Tartu
Tartu, Estonia
Demographic profile
One of the primary objectives is to describe the baseline demographic profile of patients with non-occlusive mesenteric ischemia. The demographic data will include the following information: 1. Gender (Male or Female) 2. Age (in years) 3. BMI (calculated from body weight in kilograms and height in centimeters)
Time frame: Baseline
SOFA score
Sequential Organ Failure Assessment (SOFA) score. Range: 0-24. Higher scores indicate more severe organ dysfunction.
Time frame: Baseline
Serum Lactate Levels in Patients with Non-Occlusive Mesenteric Ischemia
Serum lactate level measured in mmol/L. Higher values indicate worse tissue perfusion.
Time frame: Baseline
Baseline APACHE II Score
Acute Physiology and Chronic Health Evaluation II (APACHE II) score. Range: 0-71. Higher scores indicate more severe disease and higher predicted mortality.
Time frame: Baseline
Arterial Blood pH in Patients with Non-Occlusive Mesenteric Ischemia
Arterial pH level. Normal range is 7.35-7.45. Lower values indicate acidosis.
Time frame: Baseline
Rate of Patients Diagnosed with Non-Occlusive Mesenteric Ischemia by CT, Endoscopy, or Angiography
Percentage of participants diagnosed with non-occlusive mesenteric ischemia (NOMI) using computed tomography (CT), endoscopy, or angiography.
Time frame: Baseline
Management
Rate of surgical, conservative, endovascular or palliative management
Time frame: Baseline
30-day survival
30-day Survival of patients with non-occlusive mesenteric ischemia
Time frame: 30 days after admission
1-year survival
1-year survival of patients with non-occlusive mesenteric ischemia
Time frame: 1 year
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