The investigator would like to investigate the impact of theta-burst stimulation over left DLPFC in autism with minimally verbal ability or intellectual disability
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
60
stimulatory protocol
Chang Gung Memorial Hospital
Taoyuan District, Taiwan
Total Scores of Aberrant Behavior Checklist
Aberrant Behavior Checklist is a parents' report questionnaire for aberrant behavior. The lower scores stand for less aberrant behavior.
Time frame: Baseline, Week 4, Week 8 and Week 12
Total Scores of Emotional Dysregulation Inventory
Emotional Dysregulation Inventory is a parents' report questionnaire for emotional dysregulation. The lower scores stand for better emotional regulation.
Time frame: Baseline, Week 4, Week 8 and Week 12
Total Scores of Child Behavior Checklist
Child Behavior Checklist is a parents' report questionnaire for behavioral and emotional problems. The lower scores stand for better behavioral and emotional regulation.
Time frame: Baseline, Week 4, Week 8 and Week 12
Total Scores of Social Responsiveness Scale
Social Responsiveness Scale can measure the autism clinical severity. The lower scores stand for better social responsiveness.
Time frame: Baseline, Week 4, Week 8 and Week 12
Total Scores of Repetitive Behavior Scale-Revised
Repetitive Behavior Scale-Revised is a questionnaire that focuses on repetitive behavior. The lower scores stand for lower repetitive behavior.
Time frame: Baseline, Week 4, Week 8 and Week 12
Total Scores of Adaptive Behavior Assessment System
Adaptive Behavior Assessment System is a parents' report questionnaire for adaptive behavior. The higher scores stand for better adaptive behavior.
Time frame: Baseline, Week 4, Week 8 and Week 12
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Total Scores of Anxiety, Depression, and Mood Scale
Anxiety, Depression, and Mood Scale is a parents' report questionnaire for mental disorders (manic/ hyperactive behavior, depressed mood, social avoidance, general anxiety, obsessive/compulsive behavior) . The higher scores stand for higher mental problem.
Time frame: Baseline, Week 4, Week 8 and Week 12
Accuracy of Frith-Happe Animation
A quick and objective test of Theory of Mind. 8 questions in total, the more correct questions stand for better Social Cognition.
Time frame: Baseline, Week 4, Week 8 and Week 12
Accuracy of Eyes Task
An advanced test for Theory of Mind. 43 questions in total, the more correct questions stand for better social skills.
Time frame: Baseline, Week 4, Week 8 and Week 12
Accuracy of Wisconsin Card Sorting Test
An advanced test for cognitive flexibility. 128 questions in total, the more correct questions stand for better cognitive flexibility.
Time frame: Baseline, Week 4, Week 8 and Week 12
Accuracy of Raven's Progressive Matrices
An advanced test for for executive function. 60 questions in total, the more correct questions stand for better executive function.
Time frame: Baseline, Week 4, Week 8 and Week 12
Total Scores of Behavior Rating Inventory of Executive Function
Behavior Rating Inventory of Executive Function is a parents' report questionnaire for executive function. The lower scores stand for better executive function.
Time frame: Baseline, Week 4, Week 8 and Week 12