Upper Eyelid Dynamics in Pediatric Blepharoptosis Using High Speed Videography

Overview

Evaluation of the Upper Eyelid Dynamics in Simple Congenital Blepharoptosis before and after Levator Muscle Resection Using High speed Photography

Normal eyelid dynamics are essential for optimum performance and protection of the eye including distribution of the pre-corneal tear film, clearance of debris, stimulation of Meibomian gland secretion, and assistance of tear drainage via generating negative pressure in the lacrimal sac. Conversely, abnormal eyelid dynamics can have a variety of implications in ocular surface health and visual function.1 Current methods for evaluating eyelid dynamics include magnetic-based devices, high-speed videography, infrared videography, and direct observation.2-3 Whereas magnetic search coils are considered the gold standard for research purposes, they may not be practical at the clinical setting. Conversely, a readily available and cost-effective technology of smartphone video cameras with high speed video photography options has reached a level of perfection that may enable them to be used for objective and quantative slow motion analysis of eyelid dynamics. The interest in the study of lid dynamics started early in 1977 through dynamic measurements made with a mechanical transducer connected physically to the upper eyelid. 4 The normal spontaneous blink rate has a wide variability, ranging from 2 to 50 blinks per minute. It is reported that normal blink duration varies from 300 to 572 milliseconds. Normal blink amplitudes also vary from 7.4 to 12.8 mm and decrease with age.5-6,7-8 Most of these values have been established with different techniques for analysis with magnetic search coil.6,7,9 High-speed cameras provide precise, measurable movement detection.9 With these cameras, the upper and lower eyelids have shown to both move also horizontally during the closure phase of eyelid blinking.7 Previous studies measured the spontaneous eyelid blink dynamic changes using a high-speed camera in various conditions as age-related changes5, following upper eyelid blepharoplasty and its association with dry eye10 and in patients with thyroid disease11. Upper eyelid surgery can change the lid dynamics. For instance, incomplete lid closure is sometimes encountered after upper blepharoplasty. The most common cause of lagophthalmos is excessive skin resection, which acts as a negative passive force that is much stronger than the active closing force of the orbicularis oculi muscle and can disturb blinking .12 Congenital ptosis is the presence of an abnormally low position of the upper eyelid, with respect to the visual axis in the primary gaze .13 It may not be immediately noticeable after birth but is usually manifest within a few months. It can be unilateral or bilateral. It has a significant functional and psychosocial impact on the child.14The underlying etiology appears to be localized muscle dysgenesis. In the affected levator muscle fibers are infiltrated or replaced with fibrous and adipose tissue, which results in abnormal contraction and relaxation .15 There is an association between congenital ptosis and under action of the superior rectus muscle in up to 25% of unilateral cases and in 65% of bilateral cases .16 It may be associated with lagophthalmos on downgaze with exposure of the cornea. There is often a decreased or absent lid crease .13 Levator resection is the gold standard of surgical correction of simple congenital ptosis with fair to good levator function. It creates optimal lid contour and symmetry with relatively desirable cosmetic outcomes17-19. Lagophthalmos is one of the surgical consequences. It usually improves with time .20 In the study of Cruz et al.,2014 21 on supramaximal levator resection, spontaneous blinks were abnormal in 93% of the operated eyelids. The mean amplitude of the abnormal blinks was 37.1% of the contralateral eyelids. Downward eyelid saccades were reduced in 79% of the eyelids. To the best of our knowledge this is the first study to assess the changes of eyelid dynamics in patients with simple congenital ptosis before and after levator muscle resection using high speed video photography. Aim of the study Quantative subjective analysis of upper eyelid dynamics in patients with simple congenital ptosis before and after levator muscle resection using high speed video recording.

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