Tear Film Stability and Improvement of Asthenopia: Efficacy Observation of 0.05% Cyclosporine in Dry Eye Patients With Short BUT

Inclusion Criteria: 1. 18-75 years old (including 18 and 75 years old), male or female; 2. Meets the diagnostic criteria for dry eye syndrome in China (2020) and is mild dry eye 1) Dry Eye Questionnaire (OSDI) score ≥ 13 points; 2) BUT ≤ 10 seconds or Schirmer I ≤ 5mm/5 minutes 3) Corneal staining positive ≤ 5 points. 3. At least one of OSDI, BUT, and Schirmer I meets the moderate standard OSDI ≥ 23 points; BUT\<5 seconds; Schirmer I \< 5mm/5min 4. The subjects themselves signed an informed consent form and voluntarily participated in this study. Exclusion Criteria: 1. Women who are breastfeeding or pregnant, or men and women of childbearing age who are unable to use effective contraceptive methods during the study period; 2. Those who need to wear contact lenses during treatment; 3. Acute inflammation, infection, allergy, and trauma of the eyes; 4. There are obvious scars or keratinization on the eyelid margin; 5. Have undergone eye or eyelid surgery within the 6 months prior to enrollment; 6. Diagnosed with facial nerve paralysis or ocular nerve paralysis within 6 months prior to enrollment; 7. Currently using lacrimal duct embolization (permanent lacrimal plug or treatment with lacrimal plug within 6 months); 8. I am currently taking medication that may affect dry eye syndrome.