Benign Migratory Glossitis Associated With Antiangiogenic Drugs

Instituto do Cancer do Estado de São Paulo8 enrolled

Overview

Oral clinical descriptions related to adverse events in patients treated with those elective multi-targeted receptor tyrosine kinase inhibitors and a recombinant humanised monoclonal antibody

Electronical medical and dental records, high-resolution digital photograph were reviewed. Demographic data, medical background, clinical and laboratory information were recorded for each individual case.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Cancer Geographic Tongue

Interventions

Clinical evaluationOTHER

treatment methods, associated symptoms, evolution and clinical presentation

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * patient's charts which underwent antiangiogenic targeted drugs Exclusion Criteria: * chemoterapy without angiogenesis inhibitors

Locations (1)

Instituto do Cancer do Estado de São Paulo

São Paulo, São Paulo, Brazil

Outcomes

Primary Outcomes

Benign migratory glossitis

erythematous erosions, with loss of filiform papillae, surrounded by white circinate rims on the dorsal tongue

Time frame: From enrollment to the end of study at 7 years

Secondary Outcomes

Adverse events

Dysgeusia , dermatologic toxicities such as skin erythemas and vesicles on the palms of the hands and burning sensation

Time frame: From enrollment to the end of study at 7 years

Data from ClinicalTrials.gov

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