The objective of this clinical trial is to compare which of the two drugs best resolves symptoms in patients diagnosed with erosive and non-erosive gastroesophageal reflux disease, adult males and females. The main question is What is the proportion of patients with resolution of the main symptoms of gastroesophageal reflux disease at four weeks of treatment with pantoprazole vs tegoprazan.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
128
Tegoprazan 50 mg daily for 28 days
Pantoprazole 40 mg daily for 28 days
Gastrologen S.A. de C.V.
Mexico City, Mexico City, Mexico
RECRUITINGSaluz Investigación, S.C.
Boca del Río, Veracruz, Mexico
RECRUITINGProportion of subjects with resolution of the main symptoms of gastroesophageal reflux disease
Carlsson-Dent Questionnaire. These tool consists of 7 multiple-choice questions, using a cut-off point ≥ 4 to be considered positive, which qualitatively assesses symptoms associated with GERD and triggering factors such as diet, posture and medications used.
Time frame: From enrollment to the end of treatment at 4 weeks
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