EFFECTIVITY OF CHITOSAN COVERED GAUZE IN POSTPARTUM HEMORRHAGIC OBSTETRIC LACERATIONS

Istanbul Training and Research Hospital62 enrolled

Overview

This study was planned to investigate the efficacy of different treatment methods that can be used in the treatment of hemorrhagic tears that may occur in the postpartum period. The volunteers who will participate in the study will be evaluated during the hospitalization period after delivery and at the end of the puerperium 6 weeks after delivery, in accordance with routine postpartum control examinations. In the treatment of postpartum hemorrhagic tears, the treatment options such as suturing the tears to stop bleeding or applying tampons with bleeding stopping agent (chitosan) and compression effect to the torn area will be determined completely randomly.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Effectiveness of Chitosan Covered Gauze to Stop Bleeding in Post-partum Tears Comparison of the Effect of Chitosan Covered Gauze With Suturing in Terms of Hemostasis in Post-partum Haemorrhagic Tears

Interventions

Chitosan-covered-gauze applicationPROCEDURE

Effectiveness of chitosan-covered-gauze in terms of patients' comfort and satisfaction, hospital stay, total amount of bleeding, hemoglobin decline and other complications (infections, need for transfusion etc.) for the treatment of hemorrhagic obstetrical tears

SuturationPROCEDURE

Effectiveness of suturation in terms of patients' comfort and satisfaction, hospital stay, total amount of bleeding, hemoglobin decline and other complications (infections, need for transfusion etc.) for the treatment of hemorrhagic obstetrical tears

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 48 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Women who delivered at the Department of Obstetrics and Gynecology of Istanbul Training and Research Hospital between March 2025 and March 2027. * Age between 18 and 48 years. * Presence of a bleeding postpartum obstetric laceration (first- or second-degree) without an anatomical defect requiring surgical repair. * Absence of additional conditions that may affect the amount of postpartum bleeding, such as uterine atony or retained placental tissue. * Provision of written informed consent for participation in the study. Exclusion Criteria: * Age younger than 18 years or older than 48 years. * Absence of a bleeding postpartum first- or second-degree obstetric laceration meeting the study criteria. * Presence of an obstetric laceration with an anatomical defect requiring surgical repair. * Presence of additional causes or conditions that may affect postpartum blood loss, such as uterine atony or retained placental tissue. * Failure to provide informed consent.

Outcomes

Primary Outcomes

Amount of bleeding

Total amount of blood which is calculated by subtracting the dry weight of surgical absorbant gauze materials from their soaked weight

Time frame: From time of birth to the cessation of bleeding